Chailey Heritage are looking to raise £10,000 over a seven day period, if the target is reached then the figure will be doubled through match funding.
The charity are aiming to raise the money to purchase specialist walkers and trikes to help children and young people like three year old Faith get out of their wheelchairs.
Faith was born with a brain injury and is both visually and hearing impaired. The brain damage has also caused problems with her mobility, balance and coordination and life can be a challenge for Faith and her family, who live in Haywards Heath.
Since becoming a pupil at Chailey Heritage, Faith has been able to use a specialist trike and - supported by experienced and caring staff - it has been a real life-changer both for Faith and her family.
Mum Vicki said: "We as a family never thought that Faith would have the freedom that this specialist equipment has given her. Her communication is unique and personal to her because of her disability but what she has achieved we believe we could not get anywhere else.
"Her face when she used the trike for the first time, well I will never get that out of my head. She was so excited. She held onto the handlebars and started ringing the bell. She is able to bring the trike home which means we can all go out as a family on our bikes - something we never thought would be possible.
"For us as a family, that is priceless."
The Big Give 2022 launches at midday on Tuesday 29 November and runs until midday on Tuesday 6 December. You can donate online here